The quintessential PC real-time strategy game Command & Conquer has been re-created specifically for the N64 with new 3-D graphics and exclusive missions not available anywhere else. Westwood Studios fully redesigned the game for Nintendo 64 with new 3-D units, buildings, and terrain. Play as either the lawful Global Defense Initiative determined to uphold freedom, or the evil Brotherhood of Nod bent on total world domination. Construct bases, command armies, and develop new technologies in a battle to control the earth.

Both the Global Defense Initiative and the Brotherhood of Nod have their own characteristics and style of play. Each side has its own set of buildings, units, and tactics of war. The GDI specializes in building barracks to house infantry, while the Brotherhood of Nod is a structure that trains elite shock troops. Throughout the game, players must seek out and mine the precious mineral known as tiberium, which provides both sides with the power they need to keep their forces operational.

There are a variety of mission types in Command & Conquer. Some require an all-out assault on the opposition, while other missions demand careful planning and strategy as only a single unit is available. Players must also deal with changing terrain and the ever present "fog of war," which prevents them from viewing portions of the battlefield they have not yet explored. Support for the N64 Expansion Pak allows for enhanced graphics